Abstract
Abstract
Introduction : Dengue is a viral disease transmitted by mosquitoes of the genus Aedes, it represents a growing public health challenge in West Africa, including our country Mali, which has experienced a growing outbreak of dengue cases.1411 positive cases and 38 deaths, i.e. a lethality of 2.69% and 21 health districts were affected in 6 health regions between August 2023 and April 2024,We initiated this study in order toto assess the seroprevalence of dengue fever in the urban commune of Sikasso. Materials and Methods: This was a descriptive cross-sectional study conducted at the Medical Biology laboratory of Sikasso Hospital from June to October 2024. The Dengue Day-1 Test kit (Lot No./ Reference: ) was used for the detection of NS1 antigen, differential detection of IgM and IgG antibodies in human plasma collected in EDTA tube. Thick drop and thin smear were performed to diagnose cases of malaria associated with dengue fever. The community health centers (CSCOM) of Mancourani, Hamdallaye, Sanoubougou I and II served as collection sites. Results: We enrolled 201 samples in total, of which 19 samples were in contact with the virus, representing a prevalence of 9.46%. The female gender was predominant with a percentage of 63.16% against 36.84% of male gender. The age group [20 – 40] years was the most affected, i.e. 44.28%. The CSCOM of Mancourani recorded more positive cases. Among the clinical manifestations, fever or the notion of fever was the most reported with 83%. We had a co-infection of 31.58% between malaria and dengue.
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